Thawing and infusion of CAR-T cell products

Autores

  • Andrea Tiemi Kondo Hospital Israelita Albert Einstein
  • Lucila Nassif Kerbauy
  • Kelen Cristina Alvarez
  • Denise Cristina Oliveira
  • Andreza Alice Feitosa Ribeiro
  • Karen de Lima Prata

DOI:

https://doi.org/10.46765/2675-374X.2022v3n1p165

Palavras-chave:

CAR-T cells; thawing; infusion.

Resumo

Some patients with hematologic malignancies may benefit from chimeric antigen receptor-T (CAR-T) cell treatment. Usually, the manufacture of this cells is carried out by centralized and specialized cell therapy laboratories that cryopreserve the CAR-T cells in bags and send it for infusion in the patient treatment center. In this context, the thawing and infusion of the CAR-T cell products are critical steps in this custody chain. This article aims to discuss the most relevant points related with the CAR-T cell thawing and infusion and proposes a kind of standard operational protocol (SOP) for these processes.

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Publicado

24/04/2022

Como Citar

Kondo, A. T., Kerbauy, L. N. ., Alvarez, K. C., Oliveira, D. C. ., Ribeiro, A. A. F., & Prata, K. de L. . (2022). Thawing and infusion of CAR-T cell products. JBMTCT, 3(1), 165. https://doi.org/10.46765/2675-374X.2022v3n1p165

Edição

v. 3 n. 1 (2022): JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY

Seção

Artigos

Licença

Copyright (c) 2022 JBMTCT

Creative Commons License

Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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