Thawing and infusion of CAR-T cell products

Authors

  • Andrea Tiemi Kondo Hospital Israelita Albert Einstein
  • Lucila Nassif Kerbauy
  • Kelen Cristina Alvarez
  • Denise Cristina Oliveira
  • Andreza Alice Feitosa Ribeiro
  • Karen de Lima Prata

DOI:

https://doi.org/10.46765/2675-374X.2022v3n1p165

Keywords:

CAR-T cells; thawing; infusion.

Abstract

Some patients with hematologic malignancies may benefit from chimeric antigen receptor-T (CAR-T) cell treatment. Usually, the manufacture of this cells is carried out by centralized and specialized cell therapy laboratories that cryopreserve the CAR-T cells in bags and send it for infusion in the patient treatment center. In this context, the thawing and infusion of the CAR-T cell products are critical steps in this custody chain. This article aims to discuss the most relevant points related with the CAR-T cell thawing and infusion and proposes a kind of standard operational protocol (SOP) for these processes.

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Published

04/24/2022

How to Cite

Kondo, A. T., Kerbauy, L. N. ., Alvarez, K. C., Oliveira, D. C. ., Ribeiro, A. A. F., & Prata, K. de L. . (2022). Thawing and infusion of CAR-T cell products. JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY, 3(1), 165. https://doi.org/10.46765/2675-374X.2022v3n1p165

Issue

Vol. 3 No. 1 (2022): JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY

Section

Original article

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