Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphoblastic Leukemia - SBTMO/SOPOBE 2020 Consensus Guidelines: SBTMO/SOPOBE Guidelines: Pediatric ALL

Liane Esteves Daudt; Antonio Vaz de  Macedo; Renata Fittipaldi  Guimaraes; Virginio Climaco de Araujo  Fernandes Junior; Maura R V Ikoma  Colturato; Claudio Galvão de  Castro Junior; Luciana dos Santos  Domingues; Adriana Seber

doi:10.46765/2675-374X.2021v2n4p141

Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphoblastic Leukemia - SBTMO/SOPOBE 2020 Consensus Guidelines

SBTMO/SOPOBE Guidelines: Pediatric ALL

Authors

Liane Esteves Daudt Hospital de Clínicas de Porto Alegre - UFRGS
Antonio Vaz de Macedo 3- Hospital da Polícia Militar, Belo Horizonte, MG, Brasil
Renata Fittipaldi Guimaraes 5- Instituto de Oncologia Pediátrica IOP/GRAACC/Unifesp – São Paulo, SP Brasil
Virginio Climaco de Araujo Fernandes Junior Instituto de Oncologia Pediátrica IOP/GRAACC/Unifesp – São Paulo, SP Brasil
Maura R V Ikoma Colturato Hospital Amaral Carvalho – Jau, SP, Brasil
Claudio Galvão de Castro Junior Instituto Hemomed de Oncologia e Hematologia – São Paulo, SP, Brasil
Luciana dos Santos Domingues Hospital Samaritano – São Paulo, SP, Brasil
Adriana Seber Hospital Samaritano – São Paulo, SP, Brasil

DOI:

https://doi.org/10.46765/2675-374X.2021v2n4p141

Keywords:

Hematopoietic Stem Cell Transplantation, Pediatric Acute Lymphoblastic Leukemia, Clinical Guidelines

Abstract

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative approach to children and adolescents with high-risk acute lymphoblastic leukemia (ALL) at diagnosis or relapsed disease. Nonetheless, despite the graft versus leukemia (GVL) effect, treatment-related morbidity and mortality remains a major challenge. Moreover, the significant heterogeneity of the available data on the selection of patients, type of conditioning regimen, and type of donor hampers any definitive conclusions in the pediatric population. In 2020, the Brazilian Group for Pediatric Bone Marrow Transplantation of the Brazilian Society of Bone Marrow Transplantation and Cellular Therapy (SBTMO) and the Brazilian Society for Pediatric Oncology (SOBOPE) convened a task force to provide general guidance on HSCT for childhood ALL to providing evidence-based guidance for the appropriate management of this disease.

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Published

11/30/2021

How to Cite

Daudt, L. E., Macedo, A. V. de ., Guimaraes, R. F. ., Fernandes Junior, V. C. de A. ., Colturato, M. R. V. I. ., Castro Junior, C. G. de ., Domingues, L. dos S. ., & Seber, A. (2021). Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphoblastic Leukemia - SBTMO/SOPOBE 2020 Consensus Guidelines: SBTMO/SOPOBE Guidelines: Pediatric ALL. JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY, 2(4), 141. https://doi.org/10.46765/2675-374X.2021v2n4p141

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Vol. 2 No. 4 (2021): JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY

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