SARS-COV2 POSITIVE IN BONE MARROW TRANSPLANTATION SYMPTOMATIC PATIENTS: THE EXPERIENCE IN A SINGLE CENTER OF CEARA, BRAZIL

THE EXPERIENCE OF CEARA

Abstract

The bone marrow transplantation (BMT) recipient are susceptible to virus respiratory disease and their complications. The emergence of pandemic COVID-19, adapted their routine. We are a public school hospital bone marrow transplantation center, localized in Fortaleza/ Ceará, Northeast of Brazil. Objective: In the article we are described the asymptomatic SARS-CoV2 PCR positive in recipient pre and post bone marrow transplantation. Methods: The donors and recipients with high risk disease and selected to bone marrow transplantation in April to June are submitted a nasopharyngeal and throat swab to collected PCR multiplex SARS-CoV2. Results: We have 5 patients asymptomatic with positive results. Three allogeneic recipient and two autologous. The two inpatients follow the program because we have the result after the end of condition, we use GCSF in both and none had febrile neutropenia. Conclusion: The results show us the importance of PCR multiplex SARS-CoV2 before hospital admission to avoid bone marrow transplantation at the moment of viral load and to organized the prevention precautions. This cases are important because described patients with SARS-CoV 2 PCR positive in the early transplant with asymptomatic course.