Acute and chronic graft versus host disease after hematopoietic stem cell transplant
DOI:
https://doi.org/10.46765/2675-374X.2020v1n1p53-66Keywords:
Graft versus host disease, Hematopoietic stem cell transplantAbstract
Graft versus host disease is one of the main complications of Hematopoietic stem cell, involving about 50% to 80% of the patients. Acute GVHD clinical manifestations and therapy is discussed, as well as new NIH criteria for the diagnosis and classification of chronic GVHD. Therapy for both refractory chronic and acute GVHD is an important field of discussion once there is no superiority for the majority of the agents after primary therapy has failed. Hence, this review is meant to be a useful tool of consultation for clinicians who are dealing with this complex complication.