Collection of lymphocytes by apheresis
Keywords:cellular therapy, lymphocytapheresis, lymphocyte collection, lymphocyte donor, apheresis
The first step in the manufacturing of cell therapy products is the collection of cells from donors or patients. This point should be given special attention by all professionals involved in the development of these therapies because it is critical to guarantee the quality of the final product. Lymphocytes, especially T-cell lineage, have been used for treatment in a large number of pathologies, including oncological and infectious diseases, especially after approval by regulatory agencies in several countries for the use of Chimeric Antigen Receptor Therapies (CAR T). This article describes the steps for the procedure of collecting lymphocytes by apheresis, defining indications and contraindications as well as the planning and preparation measures for the procedure.
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